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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
Diamine oxidase from porcine kidney is a homodimer consisting of two equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose 3.3% glucosamine 2.6% N-acetylglucosamine and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.
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UC-112 is a survivin and XIAP modulator that demonstrates anticancer activity. It works by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal degradation pathway. It also reduces XIAP levels in in vivo tumor models, activates caspase-3/7 and caspase-9, and induces apoptosis in cancer cells. This product is for research use only and not for patient use.
Selectively downregulates and degrades survivin
Reduces XIAP levels in in vivo tumor models
Activates caspase-3/7 and caspase-9, inducing cancer cell apoptosis
Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
Inhibits human melanoma tumor growth in nude mice
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Chemical. CAS 426-65-3. Formula C5H5F5O2. MW 192.08. Building block for synthesis. Perfluoroalkyl carboxylate esters undergo Wittig reactions with phosphorus leading to 1-perfluoroalkyl enol ethers, which are useful precursors of various fluorinated derivatives.
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(±)-WB 4101 hydrochloride is a potent antagonist of noradrenaline. It interacts with protein in smooth muscle, promoting tight binding between the drug and receptor.
Potent antagonist of noradrenaline
Interacts with protein in smooth muscle
Promotes tight binding between the drug and receptor
Store solid form at -20°C, sealed, away from moisture
Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
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